Yes, on Disc 1, go to Episode Selection, and look for Mac Daddy. When you select it, you should see a screen with Cheese on it that asks if you want commentary on or off. Make sure you select the on option, and the insanity will commence after the title card.
Spoiler Below Best part about the commentary is when Bloo gives Cheese his chocolate milk in a glass. I like Chocolate Milk! (Commentary: Yeah, I feel ya.)