OK, I know said in the "Last movie you watched" topic that it was the last post I'd be making for a while...well, I lied. So sue me...again.
Subzeroace has hit the nail right on the head; an old-school point-and-click adventure game, in the vein of Monkey Island, Day of the Tentacle or Sam and Max, would be by the far the best format for making a Foster's videogame. RPGs and platformers are all well and good, but Foster's is not an action-based show - turning it into an action-based game dilutes the show's strengths, namely characterisation, scripting and humour, virtues which go hand-in-hand with the adventure genre. The likes of Telltale and Double Fine would be canny choices too, because I gather that they're where a lot of the talent from the early 90s LucasArts team, kings of the point-and-click adventure game, migrated to after LucasArts became "the Star Wars game factory" (nothing against Star Wars games; just that LucasArts used to be about so much more than that

). It would help that these companies are American in this case; Foster's is an American show, with a very American sense of humour. The more I think about this, the more it seems like a great idea...Foster's has such a rich variety of characters, a fantastic location in the Foster's Mansion, an infinite amount of potential plots and puzzles...if they really did this right, it would be the perfect way of creating a game that really takes advantage of what makes the show great, instead of just using its characters and settings to frame a generic videogame experience.
...but who am I kidding? For the reasons Voxxyn mentioned, there's no way it would ever happen in a million years. I guess we're stuck with churned-out, bog-standard 2D platforming from E-list development houses. Ah well.
And on that rather depressing note, I'm off on my travels. See you in a few weeks.